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Molecular biology --- Oncology. Neoplasms --- Tumors --- Oncogenes --- Gene expression --- Gene Expression Regulation --- Neoplasms --- Cell Transformation, Neoplastic --- Genetic aspects --- Congresses --- genetics --- Tumors - Genetic aspects - Congresses --- Oncogenes - Congresses --- Gene expression - Congresses --- Gene Expression Regulation - congresses --- Neoplasms - genetics - congresses --- Cell Transformation, Neoplastic - congresses --- CELL TRANSFORMATION --- NEOPLASTIC --- GENE EXPRESSION REGULATION
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Oncogenes --- Congresses --- Proto-oncogenes --- Developmental cytology --- Cell transformation --- CELLS --- GENE EXPRESSION REGULATION --- PROTO-ONCOGENES --- CONGRESSES
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Neural Tube Defects Chairwoman: Professor Judith Hall 1994 Neural tube defects are major human congenital malformations. They are the second most common cause of perinatal death owing to birth defect in the UK and lead to considerable childhood morbidity. This book contains descriptions of normal neurulation in birds, amphibians and mammals, including humans. The anatomy of neural tube defects is discussed, with emphasis on the underlying molecular genetics, particularly in mouse strains with heritable neural tube defects. There is evidence for both genetic and environmental factors in the development of neural tube defects. Possible risk factors include anticonvulsant agents, diabetes and alcohol: the current status of epidemiological studies on these is assessed and the relative contributions of potential causative elements are critically reviewed. Clinical trials in humans have shown that folic acid consumption before and immediately after conception significantly reduces the risk of having a child with a neural tube defect. The book contains a detailed description of folic acid metabolism and discussion of how it may act during neural tube closure. The book describes methods for antenatal detection and diagnosis of neural tube defects. The feasibility of treatment, both in utero and after birth, is considered. Finally, the book presents the case for implementing a programme to ensure adequate consumption of folic acid by all women of child-bearing age. Possible objections to, or disadvantages of, such a programme are discussed fully and solutions to such problems are proposed. Related Ciba Foundation Symposia: No. 156 The childhood environment and adult disease Chairman: David Barker 1991 ISBN 0 471 92957 3 No. 165 Postimplantation development in the mouse Chairwoman: Anne McLaren 1992 ISBN 0 471 93384 8 No. 182 Germline development Chairwoman: Anne McLaren 1994 ISBN 0 471 94264 2
Neural Tube Defects. --- Neural tube --- -Embryology --- Nervous system --- Acrania --- Developmental Neural Tube Defects --- Iniencephaly --- Neural Tube Developmental Defects --- Neuroenteric Cyst --- Occult Spinal Dysraphism --- Occult Spinal Dysraphism Sequence --- Tethered Spinal Cord Syndrome --- Craniorachischisis --- Developmental Defects, Neural Tube --- Diastematomyelia --- Exencephaly --- Neurenteric Cyst --- Spinal Cord Myelodysplasia --- Tethered Cord Syndrome --- Acranias --- Craniorachischises --- Cyst, Neurenteric --- Cyst, Neuroenteric --- Cysts, Neurenteric --- Cysts, Neuroenteric --- Defect, Neural Tube --- Defects, Neural Tube --- Diastematomyelias --- Dysraphism, Occult Spinal --- Dysraphisms, Occult Spinal --- Exencephalies --- Iniencephalies --- Myelodysplasia, Spinal Cord --- Myelodysplasias, Spinal Cord --- Neural Tube Defect --- Neurenteric Cysts --- Neuroenteric Cysts --- Occult Spinal Dysraphisms --- Spinal Cord Myelodysplasias --- Spinal Dysraphism, Occult --- Spinal Dysraphisms, Occult --- Tethered Cord Syndromes --- Abnormalities --- -Congresses --- Neural Tube Defects --- -Abnormalities --- Neural tube defects
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Human histology. Human cytology --- Cell adhesion --- Cell adhesion molecules
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Mice --- Embryos --- Congresses --- Development --- Developmental cytology --- Physiology --- Mice - Embryos - Congresses. --- Mice - Development - Congresses. --- Developmental cytology - Congresses. --- Mice - Embryos - Physiology - Congresses. --- EMBRYO --- GENE EXPRESSION --- MICE --- POSTIMPLANTATION PHASE --- GROWTH AND DEVELOPMENT --- CONGRESSES --- EMBRYOLOGY --- PHYSIOLOGY
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Hypothalamus --- Physiology --- Congresses --- Anatomy --- Neuroendocrinology --- Neuroanatomy --- Hypothalamus - Physiology. --- Hypothalamus - Anatomy. --- Neuroendocrinology. --- Neuroanatomy. --- HYPOTHALAMUS --- ANATOMY AND HISTOLOGY --- PHYSIOLOGY
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Consciousness --- Mind and body --- Neuropsychology --- Consciousness Disorders. --- Consciousness. --- Congresses. --- Congresses
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Germline Development Chairwoman: Anne McLaren 1994 The germline is the cell lineage that forms the link between generations and is, potentially, immortal. In animals that reproduce sexually, the germ cells undergo sexual differentiation and genetic recombination. Despite its importance, the development of the germline is an area of biology that, until recently, had been relatively neglected because of the technical difficulties associated with working with very early embryos. However, over the last few years, improved cell culture techniques, the availability of specific markers for germ cells and the identification of genes involved in germ cell specification have enabled rapid progress to be made in our understanding of the processes involved. This book links classical, cellular descriptive studies with more recent work on the molecular and genetic aspects of germline development. Contributions from some of the leading scientists in this field describe studies on a range of organisms, including insects, worms, birds, fish, amphibia, mammals and green algae. The topics covered include the specification of the germ cells, their migration to the gonads and subsequent interactions with the soma, and gametogenesis. Evolutionary aspects of germ cell segregation are also considered. Related Ciba Foundation Symposia: No. 144 Cellular basis of morphogenesis Chairman: Lewis Wolpert 1989 ISBN 0 471 92306 0 No. 165 Postimplantation development in the mouse Chairwoman: Anne McLaren 1992 ISBN 0 471 93384 8 No.181 Neural tube defects Chairwoman: Judith Hall 1994 ISBN 0 471 94172 7
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Protons --- Cell membranes --- Biological transport --- Cell Membrane --- Biological Transport --- Congresses --- metabolism --- Cells. --- Protons - Congresses --- Cell membranes - Congresses --- Biological transport - Congresses --- Cell Membrane - metabolism - congresses --- Protons - congresses --- Biological Transport - congresses --- Cells --- Hydrogen-ion concentration --- Ions --- BIOLOGICAL TRANSPORT --- PROTONS --- CELL MEMBRANE --- METABOLISM
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